Herb, Nutrient and Drug Interactions

Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies

By Mitchell Bebel Stargrove, ND, LAc, Jonathan Treasure, MA MNIMH RH (AHG) MCPP, and Dwight McKee, MD

Published by Elsevier/Mosby (2008)

  • The authoritative transdisciplinary clinical reference and teaching tool used at naturopathic, pharmacy, and Chinese medicine colleges since its publication

  • Herb-Drug Interactions
  • Drug Interactions with Vitamins, Minerals, Amino Acids and Nutraceuticals
  • Drug-Induced Nutrient Depletions

Actively engage patient choices. Be aware of risks. Integrate benefits. Offer informed options.

For decades surveys have shown that over half of patients have been regularly using vitamins, minerals, herbs and other supplements.

How do you access trusted resources to guide informed decision-making and coordinated care delivery?

This essential resource offers detailed, well-informed guidance on the therapeutic agents most frequently encountered in clinical settings and supports the safe and effective integration of herbal, nutritional, and pharmaceutical therapies. Combining pharmaceuticals with herbs or supplements can enhance or hinder a drug’s therapeutic effect—or increase the risk of adverse reactions. Drug-induced nutrient depletion is also a growing concern in clinical practice. This text provides comprehensive clinical data, quick-reference tools, and expert insight to help practitioners understand herb-drug-nutrient interactions and craft safe, individualized treatment strategies.

Herb, Nutrient and Drug Interactions

Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies

By Mitchell Bebel Stargrove, ND, LAc, Jonathan Treasure, MA MNIMH RH (AHG) MCPP, and Dwight McKee, MD

  • The authoritative transdisciplinary clinical reference and teaching tool used at naturopathic, pharmacy, and Chinese medicine colleges since its publication

  • Herb-Drug Interactions
  • Drug Interactions with Vitamins, Minerals, Amino Acids and Nutraceuticals
  • Drug-Induced Nutrient Depletions

Actively engage patient choices. Be aware of risks. Integrate benefits. Offer informed options.

For decades surveys have shown that over half of patients have been regularly using vitamins, minerals, herbs and other supplements.

How do you access trusted resources to guide informed decision-making and coordinated care delivery?

This essential resource offers detailed, well-informed guidance on the therapeutic agents most frequently encountered in clinical settings and supports the safe and effective integration of herbal, nutritional, and pharmaceutical therapies. Combining pharmaceuticals with herbs or supplements can enhance or hinder a drug’s therapeutic effect—or increase the risk of adverse reactions. Drug-induced nutrient depletion is also a growing concern in clinical practice. This text provides comprehensive clinical data, quick-reference tools, and expert insight to help practitioners understand herb-drug-nutrient interactions and craft safe, individualized treatment strategies.

Key Features

Recommended by leading educators and practitioners

“Thorough, accurate, evidence-based information that all practitioners need if they or their patients use herbs or dietary supplements. Highly recommended.”

Wayne Jonas, MD
Former Head of National Center for Complementary and Alternative Medicine, National Institutes of Health
President and Chief Executive Officer, Samueli Institute, Alexandria, Virginia
“The most comprehensive and substantiated resource I have seen on drug/herb/nutrient interactions. I was especially impressed by Dr. Stargrove and his interdisciplinary team’s ranking of the quality of the available evidence as well as their careful consideration of beneficial interactions, not just adverse effects. Required for every clinician serious about integrative medicine.”

Joseph E. Pizzorno, Jr., ND
Co-founder, President Emeritus, Bastyr University, Kenmore, Washington
Editor, Integrative Medicine: A Clinicians Journal

“It has been well documented that many patients often do not share with their practitioners all of the medicinal products they may be using. It behooves all practitioners to not only ask patients what they are taking, but also understand potential interactions and deficiencies that might occur and make recommendations. This book, by acknowledged experts in the field of integrative medicine, offers evidence-based advise for clinicians of all types. I whole-heartedly recommend this book for its thoughtful, balanced and well-referenced presentation integrating scientific evidence with practical clinical experience.”

David Riley, MD
Founder, Integrative Medicine Institute
Associate Editor, Integrative Medicine—A Clinician’s Journal
Editor, The Permanente Journal
Former Editor in Chief: Global Advances in Health and Medicine; EXPLORE – The Journal of Science and Healing; The Journal of Alternative and Complementary Medicine
Clinical Associate Professor, Univ. of New Mexico School of Medicine

Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies is by far one of my favorite interactions textbooks/databases. A team of a naturopathic physician Mitchell Stargrove, clinical herbalist Jonathan Treasure and a medical doctor Dwight McKee, left no stones unturned as they explored all potential and clinical interactions in the most commonly used herbs and vitamins. The authors utilized and shared with their readers a very specific system evaluating interactions and making this book/database essential for any healthcare practitioner interested in understanding the topic. The text is entirely evidence based and the authors provide you with a compilation of all the references to explore further. The information presented is concise and extremely practical for any clinician. This book is on a very short list of my recommended readings for my students, and should be on your bookshelf or computer screen!”

Lana Dvorkin Camiel, PharmD
Professor, Pharmacy Practice
Coordinator, Center for Drug Information and Natural Products
Massachusetts College of Pharmacy and Health Sciences University

“…. I enthusiastically welcome this book, a collaboration written by experienced clinicians within the fields of conventional, integrative and natural medicine for health professionals who wish to effectively counsel their patients on the safe and beneficial use of dietary supplements. As the title suggests, this book addresses herb-drug interactions, nutrient-drug interactions, and drug-induced nutrient depletions in a clinically oriented, and integrated manner. The authors demonstrate an appropriate balance between recommendation and risk based upon the overall strength of the scientific evidence and their own clinical experience. The text is well referenced, balanced and objective and the use of icons and summary tables allows the clinician to quickly identify areas of potential risk, as well as potential benefit. This book is a major contribution to the field of integrative medicine and an invaluable resource to practitioner and researcher alike.”

From the Foreward, by
Tieraona Low Dog, MD
Fellowship Director, Arizona Center for Integrative Medicine
Clinical Associate Professor of Medicine
University of Arizona Health Sciences Center, Tucson, AZ
Chair, United States Pharmacopeia Dietary Supplements Information Expert Panel

What Professional Journals Are Saying

Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies has been reviewed in leading professional journals across integrative, naturopathic, and biomedical fields. These reviews reflect the depth, rigor, and clinical relevance of this resource, offering insights into how it has shaped clinical practice across disciplines.

Clinical Toxicology
​​Thomas L. Kurt, MD, Consultant, Medical Toxicology
2009

Integrative Medicine: A Clinician’s Journal
John Weeks, The Integrator
Aug/Sep 2008 vol. 7 No. 4, Pg. 14

Integrative Medicine – A Clinician’s Journal
Joseph E. Pizzorno, ND
Aug/Sept 2009

Townsend Letter
Duncan Soule, MD
Aug/Sept 2009

HerbalGram
Thomas L. Kurt, MD
Clinical Professor, University of Texas Southwestern, Dallas, TX
Summer 2009

Life Extension Magazine
Michael J. Hall, ND
April 2009

British Naturopathic Journal
Roger Newman Turner, ND
2009, Vol. 26, No. 2, Pg. 10

Journal of the American Herbalists Guild
Jerry M. Cott, PhD
Review Pharmacologist/Toxicologist
Center for Drug Evaluation and Research
Division of Anesthesia, Analgesia and Rheumatology Products
U.S. Food and Drug Administration (FDA)
Spring 2009

Journal of the Society for Integrative Oncology
Stephen M. Sagar, MD
Associate Professor, McMaster University, Hamilton, Ontario, Canada
Jan 2009

The Pharmaceutical Journal
Pamela Mason, PhD, MRPharmS
November 2008

Explore
Gerald M. Lemole, MD
Christiana Care Health System, Wilmington, DE
Sept/Oct 2008 Vol. 4 No. 5 Pg. 339

Journal of the Australian Traditional-Medicine Society
Penny Robertshawe
Sept 2008

NDNR: Naturopathic News and Reviews
Stacie Deyglio, ND
Sept 2008, Pg. 22

Alternative Medicine Review
Mario Roxas, ND
Jun 2008

The Integrator
John Weeks, Editor
May, 2008

Clinical Toxicology
​​Thomas L. Kurt, MD, Consultant, Medical Toxicology
2009

Integrative Medicine: A Clinician’s Journal
John Weeks, The Integrator
Aug/Sep 2008 vol. 7 No. 4, Pg. 14

Integrative Medicine – A Clinician’s Journal
Joseph E. Pizzorno, ND
Aug/Sept 2009

Townsend Letter
Duncan Soule, MD
Aug/Sept 2009

HerbalGram
Thomas L. Kurt, MD
Clinical Professor, University of Texas Southwestern, Dallas, TX
Summer 2009

Life Extension Magazine
Michael J. Hall, ND
April 2009

British Naturopathic Journal
Roger Newman Turner, ND
2009, Vol. 26, No. 2, Pg. 10

Journal of the American Herbalists Guild
Jerry M. Cott, PhD
Review Pharmacologist/Toxicologist
Center for Drug Evaluation and Research
Division of Anesthesia, Analgesia and Rheumatology Products
U.S. Food and Drug Administration (FDA)
Spring 2009

Journal of the Society for Integrative Oncology
Stephen M. Sagar, MD
Associate Professor, McMaster University, Hamilton, Ontario, Canada
Jan 2009

The Pharmaceutical Journal
Pamela Mason, PhD, MRPharmS
November 2008

Explore
Gerald M. Lemole, MD
Christiana Care Health System, Wilmington, DE
Sept/Oct 2008 Vol. 4 No. 5 Pg. 339

Journal of the Australian Traditional-Medicine Society
Penny Robertshawe
Sept 2008

NDNR: Naturopathic News and Reviews
Stacie Deyglio, ND
Sept 2008, Pg. 22

Alternative Medicine Review
Mario Roxas, ND
Jun 2008

The Integrator
John Weeks, Editor
May, 2008

Herb, Nutrient, and Drug Interactions: Content

Published by Elsevier/Mosby (2008), the world’s leading medical publisher, this 932-page guide brings together pharmacology, nutrition, phytotherapy, and systems biology into a clear and clinically practical resource. With over 300 pages of citations, an innovative icon-based taxonomy, and 70 comprehensive monographs, Interactions remains an essential tool for healthcare professionals navigating the real-world use of supplements, herbs, and pharmaceuticals in patient care.

Aloe (Aloe vera)

Astragalus (Astragalus membranaceus)

Bilberry (Vaccinium myrtillus)

Black Cohosh (Cimicifuga racemosa)

Cascara

Cayenne (Capsicum)

Dang Gui (Angelica sinensis)

Devil’s Claw (Harpagophytum procumbens)

Echinacea (Echinacea spp.)

Eleuthero (Eleutherococcus senticosus)

Ephedra (Ephedra sinica)

Feverfew (Tanacetum parth.)

Garlic (Allium sativum)

Ginger (Zingiber off.)

Ginkgo (Ginkgo biloba)

Ginseng, Chinese/Korean (Panax ginseng)

Gotu Kola (Centella asiatica)

Green Tea (Camellia sinensis)

Hawthorn (Crataegus)

Horse Chestnut (Aesculus hippocastanum)

Kava Kava (Piper methysticum)

Licorice Root (Glycyrrhiza glabra)

Milk Thistle Seed (Silybum marianum)

Red Clover (Trifolium pratense)

Reishi Mushroom (Ganoderma lucidum)

Saw Palmetto (Serenoa repens)

St. John’s Wort (Hypericum perforatum)

Turmeric/Curcumin (Curcuma longa)

Valerian (Valeriana off.)

Vitex/Chaste (Vitex agnus-castus)

Vitamins

Beta-Carotene

Folic Acid

Vitamin A / Retinol

Vitamin B1 / Thiamine

Vitamin B2 / Riboflavin

Vitamin B3 / Niacin/Niacinamide

Vitamin B6

Vitamin B12

Vitamin C / Ascorbic Acid

Vitamin D / Calciferol

Vitamin E

Vitamin K

Minerals

Boron

Calcium

Chromium

Copper

Iron

Magnesium

Potassium

Selenium

Zinc

Amino Acids

Arginine

Carnitine

Methionine

Phenylalanine

Tryptophan

Tyrosine

Nutriceuticals and Physiologics

5-HTP (5-Hydroxytryptophan)

Alpha Lipoic Acid

Chondroitin Sulfate

Coenzyme Q10

DHEA (Dehydroepiandrosterone)

Glucosamine sulfate

Inositol

Melatonin

Omega 3 Fatty Acids (including Fish Oils: DHA and EPA)

PABA (Para-aminobenzoic Acid)

Policosanol

Probiotic Intestinal Flora and Prebiotics

S-adenosyl Methionine (SAMe)

About the Authors

Mitchell Bebel Stargrove, ND, LAc – Founder/Developer, IBIS: The Integrative BodyMind Information System; President, MedicineWorks.com/Health Resources Unlimited, Inc., Beaverton, OR, USA

Jonathan Treasure, MA, MNIMH, RH (AHG), MCPP – Centre for Natural Healing, Ashland, OR, USA

Dwight L. McKee, MD – Diplomate, American Boards of Internal Medicine, Medical Oncology, and Hematology, Aptos, CA, USA

Order Yours Today

Available through:
Professional reference tools for integrative therapeutics and natural medicine

Purchase Options

Published by: © 2008 ElsevierMosby
932 pages (8.5 x 11, two column)
Softbound

Important Note on Transactions: All purchases promoted on this site are completed through our affiliate website, VitalGoods.com. All transactions, including payment processing, shipping, downloading, returns, and data handling, are governed by VitalGoods.com’s Terms & Conditions, Privacy Policy, and Disclaimer.